| Name | Thin-layer chromatography silica gel |
| Synonyms | Silicon dioxide Thin-layer chromatography silica gel Silica gel for shallow-layer chromatography Silica gel powder for TLC (Thin Layer Chromatography) |
| Molecular Formula | mSiO2·nH2O |
| Physical and Chemical Properties | Chemical properties are white, high purity and have specified pore volume, specific surface area, pore distribution and certain particle size distribution. Soluble in hydrofluoric acid and hot concentrated alkali solution, insoluble in water or other inorganic acids. |
| Use | It is widely used in the analysis and separation of various natural and synthetic substances. At present, it has been widely used in the qualitative and quantitative analysis of the main components or trace impurities of medicine, pesticides, Chinese herbal medicine, organic chemical products, petrochemical products, grain, food, etc. and the extraction of certain substances. |
product features
thin layer chromatography silica gel is white, high purity, powdered reagent silica gel, its chemical composition is SiO2?nH2O, is a hydrogen bond type strong polar solid adsorbent, except with hydrofluoric acid, hot strong acid chemical reaction does not react with any other substances: non-toxic, tasteless, insoluble in water and organic solvents.
thin layer chromatography silica gel is a porous substance with specific pore size distribution, surface hydroxyl distribution and particle size distribution. due to the different adsorption and desorption time of different substances in the pores of the mixed system, the purpose of separation and purification is achieved. Widely used in the analysis and separation of various natural and synthetic substances. At present, thin layer chromatography silica gel has been widely used in the qualitative and quantitative analysis of the main components or trace impurities of medicine, pesticides, Chinese herbal medicine, organic chemical products, petrochemical products, grain, food, etc. and the extraction of certain substances.
Thin layer chromatography silica gel is a chemical reagent used for thin layer chromatography. Crest thin layer chromatography silica gel has narrow particle size distribution, fast separation speed, high sensitivity and resolution. Thin layer chromatography is a new simple, rapid and sensitive analysis method. This method can be used to identify the purity of substances, not only for qualitative analysis, but also for quantitative analysis.
Thin layer chromatography silica gel is mainly used for coating thin layer chromatography silica gel plate, and can also be used for qualitative or quantitative analysis of various types of organic substances. Thin layer chromatography silica gel H can be directly used as a dry cleaning agent carrier. Thin layer chromatography silica gel has been widely used in the pharmaceutical industry, phytochemistry, food chemistry, bioengineering, clinical chemical engineering, material chemistry, legal inspection analysis, environmental chemistry, life science teaching, clinical, scientific research, production and other links. The particle size, moisture, pore size, pore volume, PH, and packaging of thin layer chromatography silica gel can be customized according to user needs.
Silica gel
silica gel is synthetic silica (SiO2), which is different from natural silica (such as Shi Ying, silica, etc.). Synthetic silica is divided into hydrated silica (also known as silica) and colloidal silica-silica gel. According to the basic form of existence, silica gel is usually divided into two categories: one is silicone gel, which is a kind of hard amorphous chain and network structure of silicic acid polymer particles, which is customarily called silica gel; the other is Silica sol is a kind of silica gel that can be evenly dispersed in water.
According to the application classification, silica gel can be divided into desiccant silica gel, adsorbent silica gel, analytical silica gel, packaging and drying silica gel, catalyst carrier silica gel and special silica gel, etc.
silica gel has the characteristics of chemical inertness, large specific surface area, high internal porosity and strong adsorption capacity. It is widely used as desiccant, dehydrating agent, adsorbent, filler and catalyst carrier. It is easy to adsorb polar substances and difficult to adsorb non-polar organic substances. The moisture in the silica gel adsorption gas can reach the 50% of its own quality, while in the air flow with 60% humidity, the amount of moisture adsorbed by microporous silica gel can also reach the 24% of silica gel quality. Therefore, it is often used for drying high humidity gases. The following is a brief introduction to the main commercially available silicone products and their uses.
(1) Spherical silica gel. Spherical silica gel is a spherical particle with a particle size of 2.0~8.0mm. The specific surface area, pore volume and bulk density of spherical silica gel produced in various places have certain differences. They are mainly used for gas drying, gas adsorption, air humidity adjustment, petroleum product refining and catalyst carrier.
(2) Granular silica gel. Irregular particles with a size of 6~20mm and a specific surface area of 700~800 m2/g. It is mainly used for natural gas drying, nitrogen drying, recycled hydrogen drying and hydrocarbon separation of natural gas.
(3) water-resistant silica gel. Most of them are spherical with a specific surface area of 300~400 m2/g, which is characterized by no cracking when exposed to water. Mainly used for various gas drying, liquid saturated hydrocarbon dehydration and catalyst carrier.
(4) micropowder silica gel. The average particle size is 2~10 μm, amorphous, and the oil absorption value is 60~300g/100g. It is mainly used as an additive for food, medicine and cosmetics. Non-toxic, the amount added in food and medicine does not exceed 2%.
specifications of commonly used thin layer chromatography silica gel
1, particle size (μm)
10-40, 10-20, 20-40, 5-15, 5-10, 3-8, 0-10.
2. performance
ordinary thin layer chromatography silica gel, high efficiency thin layer chromatography silica gel.
3, type
H HF254 G GF254
H --- No chemical reagents were added.
HF254 --- add a certain amount of phosphor.
G --- Add 12-14% gypsum hemihydrate.
GF254 --- Add 12-14% hemihydrate gypsum and a certain amount of phosphor.
store
Please store the thin layer chromatography silica gel in a ventilated and dry place. Do not store it with volatile substances to avoid moisture absorption or other chemicals affecting the performance.
thin layer chromatography silica gel is packed in polyethylene plastic bottles with inner cover, 500g/bottle, and carton for outer packaging, 20 bottles per carton.
Production method
ball milling method ball milling coarse-hole block silica gel to a certain particle size, after primary bleaching precipitation for 8~10h, acid bubble for 16-24h, water washing until no chloride ion, secondary bleaching precipitation for 12h, drying until the moisture content ≤ 5%, and then screening, adding fluorescent powder to prepare thin layer chromatography silica gel.